All members of the Src gene family of tyrosine kinases are characterized by a carboxy terminal domain tyrosine which is highly phosphorylated in the inactive form of the enzyme and phosphorylated to a much lesser extent when the enzyme is active. In the case of Src p60, Y527 is this tyrosine; however, a mutant form of c-Src in which Y527 is replaced by phenylalanine is transforming and displays 5- to 10-fold elevated kinase activity compared to its normal counterpart. Csk has been identified
Human,Mouse(predicted: Rat,Chicken,Dog,Pig,Cow,Sheep,Monkey)
WB,IHC-P,IHC-F
Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.