eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with
Human,Mouse,Rat,Zebrafish(predicted: Chicken,Dog,Pig,Cow,Horse,Rabbit)
Flow-Cyt,IF
Shipped at 4℃. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.