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詳細(xì)介紹

概述
描述	Recombinant Human CEACAM1 is produced by our Mammalian expression system and the target gene encoding Gln35-Gly428 is expressed with a 6His tag at the C-terminus.
別名	Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1, Biliary Glycoprotein 1, BGP-1, CD66a, CEACAM1, BGP, BGP1
形態(tài)	Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
來(lái)源	Human Cells
氨基酸序列	QLTTESMPFNVAEGKEVLLLVHNLPLFGYSWYKGERVDGNRQIVGYAIGTATPGPANSGRE TIYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVA FTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPV TLNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFSTQELFIPNITVNNS GSYTCHANNSVTGCNRTTVKTIIVSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRW FFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENG LSPGVDHHHHHH
內(nèi)毒素水平	Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test.
Accession #	P13688

性能
背景	Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) is a member of the Carcinoembryonic Antigen (CEA) family, which belongs to the immunoglobulin superfamily. CEACAM1 is originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it is found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. CEACAM1 mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. In addition, CEACAM1 plays a important role in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses.
溶解方法	Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
保存方法	Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
純度	Greater than 95% as determined by reducing SDS-PAGE.