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目錄:愛必信(上海)生物科技有限公司>>細(xì)胞生物學(xué)>>重組蛋白>> abs04231FGF-21 (C-6His) (10ug)

FGF-21 (C-6His) (10ug)
  • FGF-21 (C-6His) (10ug)
參考價(jià) 840
訂貨量 ≥1
具體成交價(jià)以合同協(xié)議為準(zhǔn)
840
≥1
具體成交價(jià)以合同協(xié)議為準(zhǔn)
  • 品牌 absin
  • 型號(hào) abs04231
  • 廠商性質(zhì) 生產(chǎn)商
  • 所在地 上海市
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更新時(shí)間:2025-02-07 15:51:01瀏覽次數(shù):1090評(píng)價(jià)

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供貨周期 一周 規(guī)格 10ug
貨號(hào) abs04231
愛必信特色產(chǎn)品線(全部現(xiàn)貨):
二抗、標(biāo)簽抗體、對(duì)照抗體;WB相關(guān):ECL發(fā)光液、預(yù)染marker、預(yù)制膠;IHC相關(guān):二抗試劑盒、組化筆;IP/CoIP試劑盒;細(xì)胞因子、信號(hào)通路調(diào)節(jié)劑;血清、BSA、蛋白酶K、CTB、TTX、CEE;凋亡試劑盒、呼吸爆發(fā)試劑盒;動(dòng)植物提取物...
概述
描述Recombinant Cynomolgus Fibroblast Growth Factor 21 is produced by our Mammalian expression system and the target gene encoding His29-Ser209 is expressed with a 6His tag at the C-terminus.
別名FGF21; Fibroblast Growth Factor 21;FGF-21
形態(tài)Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
來源Human Cells
氨基酸序列HPIPDSSPLLQFGGQVRQRYLYTDDATEAHLEIREDGTVGGAAHQSPESLLQLKALKPGVIQI LGVKTSRFLCQKPDGALYGSLHFDPEACSFRELLLENGYNVYQSEAHGLPLHLPGNKSPHRDPAS QGPARFLPLPGLPPAPPEPPGILAPQPPDVGSSDPLSMVGPSQARSPSYASHHHHHH
內(nèi)毒素水平Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
Accession #XM_005589811.2
性能
背景Fibroblast Growth Factor 21 (FGF21) is a growth factor that belongs to the FGF family. FGF family proteins play a central role during prenatal development and postnatal growth and regeneration of mamy tissues, by promoting cellular proliferation and differentiation. FGF21 is a potent activator of glucose uptake on adipocytes, protects animal from diet-induced obesity when overexpression in transgenic mice, and lower blood glucose and triglyceride levels when therapeutically adiministered to diabetic redents. FGF21 is produced by hepatocytes in reponse to free fatty acid stimulation of a PPARa/RXR dimeric complex. This situation occurs clinically during starvation, or following the ingestionof a highly-fat/low-carbohydrate diet. Upon FGF21 secretion, white adipose tissue is induced to release free fatty acids from triglyceride stores. Once free fatty acid reach hepatocytes, they are oxidized and reduced to acetyl-CoA. The acetyl-CoA is recombined into 4-carbon ketone bodies, release, and transported to peripheral tissue for TCA processing and energy generation.
溶解方法Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
保存方法Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
純度Greater than 95% as determined by reducing SDS-PAGE.

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